NSMCE2, a novel super-enhancer-regulated gene, is linked to poor prognosis and therapy resistance in breast cancer

Abstract Background Despite today’s advances in the treatment of cancer, breast cancer-related mortality remains high, in part due to the lack of effective targeted therapies against breast tumor types that do not respond to standard treatments. Therefore, identifying additional breast cancer molecu...

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Bibliographic Details
Main Authors: Carolina Di Benedetto, Justin Oh, Zainab Choudhery, Weiquan Shi, Gilmer Valdes, Paola Betancur
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-10157-7