Genetic origin of patients having spastic paraplegia with or without other neurologic manifestations

Genetic origin of patients having spastic paraplegia with or without other neurologic manifestations

Abstract Background Hereditary spastic paraplegia (HSP) is a group of neurodegenerative diseases characterized by lower-limb spastic paraplegia with highly genetic and clinical heterogeneity. However, the clinical sign of spastic paraplegia can also be seen in a variety of hereditary neurologic dise...

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Bibliographic Details
Main Authors: Jiannan Chen, Zhe Zhao, Hongrui Shen, Qi Bing, Nan Li, Xuan Guo, Jing Hu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Neurology
Subjects:
Hereditary spastic paraplegia
Leukodystrophy
Homocysteine remethylation disorders
Hereditary ataxia
Charcot-Marie-tooth atrophy
Genetic analysis
Online Access:https://doi.org/10.1186/s12883-022-02708-z

Internet

https://doi.org/10.1186/s12883-022-02708-z

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