Loss of Vhl alters trabecular bone loss during S. aureus osteomyelitis in a cell-specific manner

Loss of Vhl alters trabecular bone loss during S. aureus osteomyelitis in a cell-specific manner

Osteomyelitis, or bone infection, is a major complication of accidental trauma or surgical procedures involving the musculoskeletal system. Staphylococcus aureus is the most frequently isolated pathogen in osteomyelitis and triggers significant bone loss. Hypoxia-inducible factor (HIF) signaling has...

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Bibliographic Details
Main Authors: Caleb A. Ford, Ian M. Hurford, Laura E. Fulbright, Jacob M. Curry, Christopher T. Peek, Thomas J. Spoonmore, Virginia Cruz Victorio, Joshua R. Johnson, Sun H. Peck, James E. Cassat
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
osteomyelitis (OM)
Staphylococcus aureus
infection
HIF signaling
von Hippel-Lindau (VHL)
cre-lox approach
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.985467/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.985467/full

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