Predictive modelling and simulation for taming the chance and luck in biologics drug discovery
Three Pillars of Survival paradigm in the pharmaceutical drug discovery stipulates that a drug candidate is more likely to reach Phase III if it meets the following criteria: 1) it reaches the required tissue compartment, 2) engages the desired target, 3) triggers the desired downstream pharmacologi...
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Format: | Article |
Language: | English |
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Estonian Academy Publishers
2023-10-01
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Series: | Proceedings of the Estonian Academy of Sciences |
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Online Access: | https://kirj.ee/wp-content/plugins/kirj/pub/proc-4-2023-371-381_20231024125333.pdf |