Predictive modelling and simulation for taming the chance and luck in biologics drug discovery

Three Pillars of Survival paradigm in the pharmaceutical drug discovery stipulates that a drug candidate is more likely to reach Phase III if it meets the following criteria: 1) it reaches the required tissue compartment, 2) engages the desired target, 3) triggers the desired downstream pharmacologi...

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Bibliographic Details
Main Author: Armin Sepp
Format: Article
Language:English
Published: Estonian Academy Publishers 2023-10-01
Series:Proceedings of the Estonian Academy of Sciences
Subjects:
Online Access:https://kirj.ee/wp-content/plugins/kirj/pub/proc-4-2023-371-381_20231024125333.pdf

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