Biomimetic and NOS‐Responsive Nanomotor Deeply Delivery a Combination of MSC‐EV and Mitochondrial ROS Scavenger and Promote Heart Repair and Regeneration

Biomimetic and NOS‐Responsive Nanomotor Deeply Delivery a Combination of MSC‐EV and Mitochondrial ROS Scavenger and Promote Heart Repair and Regeneration

Abstract Mesenchymal stem cell‐derived extracellular vesicle (MSC‐EV) is shown to promote cardiac repair, however, it still falls short in initiating myocardia proliferation restart. In this regard, ROS‐induced DNA damage and responses are the culprit of cellcycle arrest. Here, this work constructs...

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Bibliographic Details
Main Authors: Ning Zhang, Mengkang Fan, Yongchao Zhao, Xiaolong Hu, Qiongjun Zhu, Xiaolu Jiao, Qingbo Lv, Duanbin Li, Zheyong Huang, Guosheng Fu, Junbo Ge, Hongjun Li, Wenbin Zhang
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Advanced Science
Subjects:
biomimetic
cardiac repair
drug delivery
extracellular vesicle
nanomotors
Online Access:https://doi.org/10.1002/advs.202301440

Internet

https://doi.org/10.1002/advs.202301440

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