Ketamine alters behavior and decreases BDNF levels in the rat brain as a function of time after drug administration

Ketamine alters behavior and decreases BDNF levels in the rat brain as a function of time after drug administration

Objective: To evaluate behavioral changes and brain-derived neurotrophic factor (BDNF) levels in rats subjected to ketamine administration (25 mg/kg) for 7 days. Method: Behavioral evaluation was undertaken at 1 and 6 hours after the last injection. Results: We observed hyperlocomotion 1 hour af...

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Bibliografische gegevens
Hoofdauteurs: Daiane B. Fraga, Gislaine Z. Réus, Helena M. Abelaira, Renata D. De Luca, Leila Canever, Bianca Pfaffenseller, Gabriela D. Colpo, Flávio Kapczinski, João Quevedo, Alexandra I. Zugno
Formaat: Artikel
Taal:English
Gepubliceerd in: Associação Brasileira de Psiquiatria (ABP) 2013-09-01
Reeks:Brazilian Journal of Psychiatry
Onderwerpen:
Brain-derived-neurotrophic factor
forced swimming test
behavioral
ketamine
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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462013000300262&lng=en&tlng=en

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