Molecular characteristics of microsatellite stable early-onset colorectal cancer as predictors of prognosis and immunotherapeutic response

Molecular characteristics of microsatellite stable early-onset colorectal cancer as predictors of prognosis and immunotherapeutic response

Abstract The incidence of early-onset colorectal cancer (EO-CRC, in patients younger than 50) is increasing worldwide. The specific gene signatures in EO-CRC patients are largely unknown. Since EO-CRC with microsatellite instability is frequently associated with Lynch syndrome, we aimed to comprehen...

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Bibliographic Details
Main Authors: Can Lu, Xiaopeng Zhang, Josefine Schardey, Ulrich Wirth, Kathrin Heinrich, Luca Massiminio, Giulia Martina Cavestro, Jens Neumann, Alexandr V. Bazhin, Jens Werner, Florian Kühn
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00414-8

Internet

https://doi.org/10.1038/s41698-023-00414-8

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