Molecular characteristics of microsatellite stable early-onset colorectal cancer as predictors of prognosis and immunotherapeutic response
Abstract The incidence of early-onset colorectal cancer (EO-CRC, in patients younger than 50) is increasing worldwide. The specific gene signatures in EO-CRC patients are largely unknown. Since EO-CRC with microsatellite instability is frequently associated with Lynch syndrome, we aimed to comprehen...
Main Authors: | Can Lu, Xiaopeng Zhang, Josefine Schardey, Ulrich Wirth, Kathrin Heinrich, Luca Massiminio, Giulia Martina Cavestro, Jens Neumann, Alexandr V. Bazhin, Jens Werner, Florian Kühn |
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格式: | 文件 |
语言: | English |
出版: |
Nature Portfolio
2023-07-01
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丛编: | npj Precision Oncology |
在线阅读: | https://doi.org/10.1038/s41698-023-00414-8 |
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