Myeloid-associated differentiation marker is a novel SP-A-associated transmembrane protein whose expression on airway epithelial cells correlates with asthma severity

Abstract Surfactant protein A (SP-A) is well-known for its protective role in pulmonary immunity. Previous studies from our group have shown that SP-A mediates eosinophil activities, including degranulation and apoptosis. In order to identify potential binding partners on eosinophils for SP-A, eosin...

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Bibliographic Details
Main Authors: Alane Blythe C. Dy, Paul R. Langlais, Natalie K. Barker, Kenneth J. Addison, Sasipa Tanyaratsrisakul, Scott Boitano, Stephanie A. Christenson, Monica Kraft, Deborah Meyers, Eugene R. Bleecker, Xingnan Li, Julie G. Ledford
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-02869-w