Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters

The successful development of a chemoprophylaxis against SARS-CoV-2 could provide a tool for infection prevention that is implementable alongside vaccination programmes. Nafamostat is a serine protease inhibitor that inhibits SARS-CoV-2 entry in vitro, but it has not been characterised for chemoprop...

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Main Authors: Megan Neary, Joanne Sharp, Eduardo Gallardo-Toledo, Joanne Herriott, Edyta Kijak, Chloe Bramwell, Helen Cox, Lee Tatham, Helen Box, Paul Curley, Usman Arshad, Rajith K. R. Rajoli, Henry Pertinez, Anthony Valentijn, Kevin Dhaliwal, Frank Mc Caughan, James Hobson, Steve Rannard, Anja Kipar, James P. Stewart, Andrew Owen
格式: 文件
语言:English
出版: MDPI AG 2023-08-01
丛编:Viruses
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在线阅读:https://www.mdpi.com/1999-4915/15/8/1744