Systematic identification of CDC34 that functions to stabilize EGFR and promote lung carcinogenesis

Systematic identification of CDC34 that functions to stabilize EGFR and promote lung carcinogenesis

Background: How the oncoprotein epidermal growth factor receptor (EGFR) evades proteolytic degradation and accumulates in non-small cell lung cancer (NSCLC) remains unclear, and ubiquitin pathway genes (UPGs) that are critical to NSCLC needs to be systematically identified. Methods: A total of 696 U...

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Bibliographic Details
Main Authors: Xin-Chun Zhao, Gui-Zhen Wang, Zhe-Sheng Wen, Yong-Chun Zhou, Qian Hu, Bin Zhang, Li-Wei Qu, San-Hui Gao, Jie Liu, Liang Ma, Yan-Fei Zhang, Chen Zhang, Hong Yu, Da-Lin Zhang, Min Wang, Chang-Li Wang, Yun-Chao Huang, Zhi-hua Liu, Yong Zhao, Liang Chen, Guang-Biao Zhou
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300645

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http://www.sciencedirect.com/science/article/pii/S2352396420300645

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