Automated classification of protein subcellular localization in immunohistochemistry images to reveal biomarkers in colon cancer

Abstract Background Protein biomarkers play important roles in cancer diagnosis. Many efforts have been made on measuring abnormal expression intensity in biological samples to identity cancer types and stages. However, the change of subcellular location of proteins, which is also critical for under...

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Bibliographic Details
Main Authors: Zhen-Zhen Xue, Yanxia Wu, Qing-Zu Gao, Liang Zhao, Ying-Ying Xu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-03731-y