Direct comparison of distinct naive pluripotent states in human embryonic stem cells

Human embryonic stem cells (hESCs) in culture display a state of primed pluripotency, but recent protocols have been developed that enable hESCs to adopt a naive-like pluripotent state. Here the authors perform a side-by-side comparison of methods used to culture naive hESCs and confirm the role of...

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Bibliographic Details
Main Authors: S. Warrier, M. Van der Jeught, G. Duggal, L. Tilleman, E. Sutherland, J. Taelman, M. Popovic, S. Lierman, S. Chuva De Sousa Lopes, A. Van Soom, L. Peelman, F. Van Nieuwerburgh, D. I. M. De Coninck, B. Menten, P. Mestdagh, J. Van de Sompele, D. Deforce, P. De Sutter, B. Heindryckx
Format: Article
Language:English
Published: Nature Portfolio 2017-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15055