Establishment of a transgene-free iPS cell line (SDQLCHi046-A) from a young patient bearing a HDAC8 mutation and suffering from Cornelia de Lange Syndrome

Establishment of a transgene-free iPS cell line (SDQLCHi046-A) from a young patient bearing a HDAC8 mutation and suffering from Cornelia de Lange Syndrome

In this study, peripheral blood mononuclear cells were isolated from a young male patient bearing a histone deacetyl-lase 8 (HDAC8) mutation and suffering from Cornelia de Lange Syndrome verified by clinical and genetic diagnosis. Induced pluripotent stem cells (iPSCs) were established by a non-inte...

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Bibliographic Details
Main Authors: Zilong Li, Chen Liu, Hongmei Xin, Yanan Yang, Yanxin Wang, Shasha Niu, Chunlai Gao, Zhongtao Gai, Yi Liu
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Stem Cell Research
Subjects:
iPSC
Reprogramming
HDAC8
CdLS
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122003336

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http://www.sciencedirect.com/science/article/pii/S1873506122003336

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