Targeting Extracellular Vesicles to the Arthritic Joint Using a Damaged Cartilage-Specific Antibody
The targeted delivery of therapies to diseased tissues offers a safe opportunity to achieve optimal efficacy while limiting systemic exposure. These considerations apply to many disease indications but are especially relevant for rheumatoid arthritis (RA), as RA is a systemic autoimmune disease whic...
Main Authors: | Louise M. Topping, Bethan L. Thomas, Hefin I. Rhys, Jordi L. Tremoleda, Martyn Foster, Michael Seed, Mathieu-Benoit Voisin, Chiara Vinci, Hannah L. Law, Mauro Perretti, Lucy V. Norling, Helena S. Azevedo, Ahuva Nissim |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-02-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2020.00010/full |
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