Vitamin D Enhances Immune Effector Pathways of NK Cells Thus Providing a Mechanistic Explanation for the Increased Effectiveness of Therapeutic Monoclonal Antibodies

Vitamin D Enhances Immune Effector Pathways of NK Cells Thus Providing a Mechanistic Explanation for the Increased Effectiveness of Therapeutic Monoclonal Antibodies

Patients with diffuse large cell lymphoma who have an adequate vitamin D supply derive significantly more benefit from immuno-chemotherapy with rituximab than patients with vitamin D deficiency; this is especially true for female patients. We have already been able to show that vitamin D increases t...

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Bibliographic Details
Main Authors: Konstantinos Christofyllakis, Frank Neumann, Moritz Bewarder, Lorenz Thurner, Dominic Kaddu-Mulindwa, Igor Age Kos, Vadim Lesan, Joerg Thomas Bittenbring
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Nutrients
Subjects:
vitamin D
lymphoma
rituximab
antibody-dependent cellular cytotoxicity
natural killer cells
interferon alpha
Online Access:https://www.mdpi.com/2072-6643/15/16/3498

Internet

https://www.mdpi.com/2072-6643/15/16/3498

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