Evaluating the role of IDO1 macrophages in immunotherapy using scRNA-seq and bulk-seq in colorectal cancer

Evaluating the role of IDO1 macrophages in immunotherapy using scRNA-seq and bulk-seq in colorectal cancer

BackgroundMacrophage infiltration is crucial for colorectal cancer (CRC) immunotherapy. Detailed classification of macrophage subsets will facilitate the selection of patients suitable for immunotherapy. However, the classification of macrophages in CRC is not currently detailed.MethodsIn this study...

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Bibliographic Details
Main Authors: Xingwu Liu, Guanyu Yan, Boyang Xu, Han Yu, Yue An, Mingjun Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
colorectal cancer (CRC)
macrophage
tumor immunity
immunotherapy
single-cell RNA sequencing (scRNA-seq)
IDO1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1006501/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1006501/full

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