Carboxylated Poly-<span style="font-variant: small-caps">l</span>-Lysine as a Macromolecular Cryoprotective Agent Enables the Development of Defined and Xeno-Free Human Sperm Cryopreservation Reagents

Carboxylated Poly-<span style="font-variant: small-caps">l</span>-Lysine as a Macromolecular Cryoprotective Agent Enables the Development of Defined and Xeno-Free Human Sperm Cryopreservation Reagents

In human sperm cryopreservation, test yolk buffer and human serum albumin have been used as permeating macromolecular-weight cryoprotectants. In clinical reproductive medicine, human serum albumin is frequently used because of low risks of zoonoses and allergic reactions. However, the risk of alloge...

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Bibliographic Details
Main Authors: Hiroki Takeuchi, Mikiko Nishioka, Tadashi Maezawa, Yuko Kitano, Kento Terada-Yoshikawa, Ryota Tachibana, Manabu Kato, Suong-hyu Hyon, Yuki Gen, Kayo Tanaka, Kuniaki Toriyabe, Masafumi Nii, Eiji Kondo, Tomoaki Ikeda
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
xeno-free and defined
cryopreservation reagent
low-molecular-weight cryoprotective agents
macromolecular-weight cryoprotective agents
saccharides
Online Access:https://www.mdpi.com/2073-4409/10/6/1435

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https://www.mdpi.com/2073-4409/10/6/1435

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