Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery

Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery

Enteroviruses are a leading cause of upper respiratory tract, gastrointestinal, and neurological infections. Management of enterovirus-related diseases has been hindered by the lack of specific antiviral treatment. The pre-clinical and clinical development of such antivirals has been challenging, ca...

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Bibliographic Details
Main Authors: Fatma Masmoudi, Nanci Santos-Ferreira, Dasja Pajkrt, Katja C. Wolthers, Jeroen DeGroot, Maria L. H. Vlaming, Joana Rocha-Pereira, Ludovico Buti
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
enterovirus
organoids
antivirals
intestinal
Online Access:https://www.mdpi.com/2073-4409/12/8/1138

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https://www.mdpi.com/2073-4409/12/8/1138

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