Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells.

Stromal cells such as myofibroblasts influence tumor progression. The mechanisms are unclear but may involve effects on both tumor cells and recruitment of bone marrow-derived mesenchymal stromal cells (MSCs) which then colonize tumors. Using iTRAQ and LC-MS/MS we identified the adipokine, chemerin,...

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Bibliographic Details
Main Authors: J Dinesh Kumar, Chris Holmberg, Sandhir Kandola, Islay Steele, Peter Hegyi, Laszlo Tiszlavicz, Rosalind Jenkins, Robert J Beynon, David Peeney, Olivier T Giger, Ahlam Alqahtani, Timothy C Wang, Trevor T Charvat, Mark Penfold, Graham J Dockray, Andrea Varro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4134237?pdf=render