Quantitative structure-activity relationship (QSAR) modelling study of some novel carboxamide series as new anti-tubercular agents

Quantitative structure-activity relationship (QSAR) modelling study of some novel carboxamide series as new anti-tubercular agents

Abstract Background QSAR modelling was performed on thirty-five (35) newly discovered compounds of N-(2-phenoxy) ethyl imidazo[1,2-a] pyridine-3-carboxamide (IPA) to predict their biological activities against Mycobacterium tuberculosis (MTB-H37Rv strain) by using some numerical data derived from st...

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Bibliographic Details
Main Authors: Mustapha Abdullahi, Shola Elijah Adeniji, David Ebuka Arthur, Shuaibu Musa
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:Bulletin of the National Research Centre
Subjects:
QSAR
Template
Docking
Hydrogen bonding
Genetic algorithm
Multi-linear regression
Online Access:http://link.springer.com/article/10.1186/s42269-020-00389-7

Internet

http://link.springer.com/article/10.1186/s42269-020-00389-7

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