Grafted human-induced pluripotent stem cells-derived oligodendrocyte progenitor cells combined with human umbilical vein endothelial cells contribute to functional recovery following spinal cord injury

Abstract Background Spinal cord injury (SCI) is a devastating disease that causes extensive damage to oligodendrocytes and neurons leading to demyelination and axonal degeneration. In this study, we co-transplanted cell grafts containing oligodendrocyte progenitor cells (OPCs) derived from human-ind...

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Bibliographic Details
Main Authors: Qian Li, Sumei Liu, Tianqi Zheng, Mo Li, Boling Qi, Liping Zhou, Bochao Liu, Dan Ma, Chao Zhao, Zhiguo Chen
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-024-03651-1