Impaired Functional T-Cell Response to SARS-CoV-2 After Two Doses of BNT162b2 mRNA Vaccine in Older People

Impaired Functional T-Cell Response to SARS-CoV-2 After Two Doses of BNT162b2 mRNA Vaccine in Older People

Long-term care facility (LTCF) older residents display physiological alterations of cellular and humoral immunity that affect vaccine responses. Preliminary reports suggested a low early postvaccination antibody response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim o...

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Bibliographic Details
Main Authors: Julie Demaret, Bénédicte Corroyer-Simovic, Enagnon Kazali Alidjinou, Anne Goffard, Jacques Trauet, Sophie Miczek, Fanny Vuotto, Arnaud Dendooven, Dominique Huvent-Grelle, Juliette Podvin, Daniel Dreuil, Karine Faure, Dominique Deplanque, Laurence Bocket, Alain Duhamel, Julien Labreuche, Annie Sobaszek, Michael Hisbergues, Francois Puisieux, Myriam Labalette, Guillaume Lefèvre
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
SARS – CoV – 2
vaccine
older people and ageing
T cells response
mRNA vaccination
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.778679/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.778679/full

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