Akkermansia muciniphila inhibits nonalcoholic steatohepatitis by orchestrating TLR2-activated γδT17 cell and macrophage polarization

Akkermansia muciniphila inhibits nonalcoholic steatohepatitis by orchestrating TLR2-activated γδT17 cell and macrophage polarization

ABSTRACTCurrent evidence indicates that the next-generation probiotic Akkermansia muciniphila (A. muciniphila) has therapeutic potential for nonalcoholic fatty liver disease (NAFLD), especially its inflammatory stage known as nonalcoholic steatohepatitis (NASH). However, the mechanisms of A. mucinip...

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Bibliographic Details
Main Authors: Yuqiu Han, Qi Ling, Li Wu, Xiaosen Wang, Zhifei Wang, Jun Chen, Zhipeng Zheng, Ziyuan Zhou, Longfei Jia, Lanjuan Li, Baohong Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
NASH
Akkermansia muciniphila
TLR2
γδt cells
macrophages
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2221485

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2023.2221485

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