Analysis of Serum Advanced Glycation Endproducts Reveals Methylglyoxal-Derived Advanced Glycation MG-H1 Free Adduct Is a Risk Marker in Non-Diabetic and Diabetic Chronic Kidney Disease

Analysis of Serum Advanced Glycation Endproducts Reveals Methylglyoxal-Derived Advanced Glycation MG-H1 Free Adduct Is a Risk Marker in Non-Diabetic and Diabetic Chronic Kidney Disease

Accumulation of advanced glycation endproducts (AGEs) is linked to decline in renal function, particularly in patients with diabetes. Major forms of AGEs in serum are protein-bound AGEs and AGE free adducts. In this study, we assessed levels of AGEs in subjects with and without diabetes, with normal...

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Bibliographic Details
Main Authors: Naila Rabbani, Antonysunil Adaikalakoteswari, James R. Larkin, Sianna Panagiotopoulos, Richard J. MacIsaac, Dennis K. Yue, Gregory R. Fulcher, Matthew A. Roberts, Merlin Thomas, Elif Ekinci, Paul J. Thornalley
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
chronic kidney disease
diabetes
glycation
methylglyoxal
estimated glomerular filtration rate
Online Access:https://www.mdpi.com/1422-0067/24/1/152

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https://www.mdpi.com/1422-0067/24/1/152

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