Clofibrate Attenuates ROS Production by Lipid Overload in Cultured Rat Hepatoma Cells

PURPOSE: To investigate the effect of clofibrate on inducing liver fatty acid binding protein (FABP1) following a high-fat load in a hepatocyte cell culture model. METHODS: Rat hepatoma cells (CRL-1548) were treated with a fatty acid (FA) mixture consisting of oleate:palmitate (2:1) in the presence...

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Bibliographic Details
Main Authors: Yufei Chen, Wei Li, Guqi Wang, Frank J Burczynski
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/27193