A novel function and mechanism of ischemia-induced retinal astrocyte-derived exosomes for RGC apoptosis of ischemic retinopathy

A novel function and mechanism of ischemia-induced retinal astrocyte-derived exosomes for RGC apoptosis of ischemic retinopathy

Retinal ischemia is a common clinical event leading to retinal ganglion cell (RGC) death, resulting in irreversible vision loss. In the retina, glia-neuron communication is crucial for multiple functions and homeostasis. Extracellular vesicles, notably exosomes, play a critical role. The functions a...

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Bibliographic Details
Main Authors: Xiaoyuan Ye, Yunfei Liu, Congying Chen, Yimeng Sun, Fan Li, Yunzhao Fu, Jiawen Luo, Lishi Su, Wei Chi
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Non-coding RNAs
retinal ischemia
astrocytes
exosomes
microRNA
MAPK8
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253124000969

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http://www.sciencedirect.com/science/article/pii/S2162253124000969

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