Interactions between calmodulin and neurogranin govern the dynamics of CaMKII as a leaky integrator.

Calmodulin-dependent kinase II (CaMKII) has long been known to play an important role in learning and memory as well as long term potentiation (LTP). More recently it has been suggested that it might be involved in the time averaging of synaptic signals, which can then lead to the high precision of...

Full description

Bibliographic Details
Main Authors: Mariam Ordyan, Tom Bartol, Mary Kennedy, Padmini Rangamani, Terrence Sejnowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008015&type=printable