Quantitative models for the inference of intratumor heterogeneity

Abstract Intratumor heterogeneity (ITH) is an omnipresent property of cancers and predicts poor survival in most types of cancer. The propensity to metastasize and the regrowth of tumors after therapy are both associated with ITH. Quantification of the level of ITH in a malignancy is hence of great...

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Bibliographic Details
Main Authors: Tom van denBosch, Louis Vermeulen, Daniël M. Miedema
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Computational and Systems Oncology
Subjects:
Online Access:https://doi.org/10.1002/cso2.1034