The Discovery of Novel Agents against <i>Staphylococcus aureus</i> by Targeting Sortase A: A Combination of Virtual Screening and Experimental Validation
<i>Staphylococcus aureus (S. aureus)</i>, commonly known as “superbugs”, is a highly pathogenic bacterium that poses a serious threat to human health. There is an urgent need to replace traditional antibiotics with novel drugs to combat <i>S. aureus</i>. Sortase A (SrtA) is a...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-12-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/17/1/58 |