Computational prediction and experimental validation of Salmonella Typhimurium SopE-mediated fine-tuning of autophagy in intestinal epithelial cells

Macroautophagy is a ubiquitous homeostasis and health-promoting recycling process of eukaryotic cells, targeting misfolded proteins, damaged organelles and intracellular infectious agents. Some intracellular pathogens such as Salmonella enterica serovar Typhimurium hijack this process during pathoge...

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Bibliographic Details
Main Authors: Amanda Demeter, Anne-Claire Jacomin, Lejla Gul, Ashleigh Lister, James Lipscombe, Rachele Invernizzi, Priscilla Branchu, Iain Macaulay, Ioannis P. Nezis, Robert A. Kingsley, Tamas Korcsmaros, Isabelle Hautefort
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.834895/full