EGFR related mutational status and association to clinical outcome of third-line cetuximab-irinotecan in metastatic colorectal cancer

<p>Abstract</p> <p>Background</p> <p>As supplement to <it>KRAS </it>mutational analysis<it>, BRAF and PIK3CA </it>mutations as well as expression of PTEN may account for additional non-responders to anti-EGFR-MoAbs treatment. The aim of the prese...

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Bibliographic Details
Main Authors: Frifeldt Sanne K, Lindebjerg Jan, Pallisgaard Niels, Spindler Karen-Lise G, Jakobsen Anders
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/11/107