Polyamine Transport Assay Using Reconstituted Yeast Membranes

ATP13A2/PARK9 is a late endo-/lysosomal P5B transport ATPase that is associated with several neurodegenerative disorders. We recently characterized ATP13A2 as a lysosomal polyamine exporter, which sheds light on the molecular identity of the unknown mammalian polyamine transport system. Here, we des...

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Bibliographic Details
Main Authors: Sarah Veen, Shaun Martin, Marleen Schuermans, Peter Vangheluwe
Format: Article
Language:English
Published: Bio-protocol LLC 2021-01-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=3888&type=0