High throughput micro-well generation of hepatocyte micro-aggregates for tissue engineering.

High throughput micro-well generation of hepatocyte micro-aggregates for tissue engineering.

The main challenge in hepatic tissue engineering is the fast dedifferentiation of primary hepatocytes in vitro. One successful approach to maintain hepatocyte phenotype on the longer term is the cultivation of cells as aggregates. This paper demonstrates the use of an agarose micro-well chip for the...

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Bibliographic Details
Main Authors: Elien Gevaert, Laurent Dollé, Thomas Billiet, Peter Dubruel, Leo van Grunsven, Aart van Apeldoorn, Ria Cornelissen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136852?pdf=render

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http://europepmc.org/articles/PMC4136852?pdf=render

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