Albumin-Mediated Size Exclusion Chromatography: The Apparent Molecular Weight of PSMA Radioligands as Novel Parameter to Estimate Their Blood Clearance Kinetics
A meticulously adjusted pharmacokinetic profile and especially fine-tuned blood clearance kinetics are key characteristics of therapeutic radiopharmaceuticals. We, therefore, aimed to develop a method that allowed the estimation of blood clearance kinetics in vitro. For this purpose, <sup>177&...
| Main Authors: | , , , |
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| 格式: | 文件 |
| 语言: | English |
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MDPI AG
2022-09-01
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| 丛编: | Pharmaceuticals |
| 主题: | |
| 在线阅读: | https://www.mdpi.com/1424-8247/15/9/1161 |