Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight

Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight

Abstract As spaceflight becomes more common with commercial crews, blood-based measures of crew health can guide both astronaut biomedicine and countermeasures. By profiling plasma proteins, metabolites, and extracellular vesicles/particles (EVPs) from the SpaceX Inspiration4 crew, we generated “spa...

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Bibliographic Details
Main Authors: Nadia Houerbi, JangKeun Kim, Eliah G. Overbey, Richa Batra, Annalise Schweickart, Laura Patras, Serena Lucotti, Krista A. Ryon, Deena Najjar, Cem Meydan, Namita Damle, Christopher Chin, S. Anand Narayanan, Joseph W. Guarnieri, Gabrielle Widjaja, Afshin Beheshti, Gabriel Tobias, Fanny Vatter, Jeremy Wain Hirschberg, Ashley Kleinman, Evan E. Afshin, Matthew MacKay, Qiuying Chen, Dawson Miller, Aaron S. Gajadhar, Lucy Williamson, Purvi Tandel, Qiu Yang, Jessica Chu, Ryan Benz, Asim Siddiqui, Daniel Hornburg, Steven Gross, Bader Shirah, Jan Krumsiek, Jaime Mateus, Xiao Mao, Irina Matei, Christopher E. Mason
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-48841-w

Internet

https://doi.org/10.1038/s41467-024-48841-w

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