The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse

The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse

Objective: Type 2 diabetes (T2D) occurs by deterioration in pancreatic β-cell function and/or progressive loss of pancreatic β-cell mass under the context of insulin resistance. α7 nicotinic acetylcholine receptor (nAChR) may contribute to insulin sensitivity but its role in the pathogenesis of T2D...

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Bibliographic Details
Main Authors: Blandine Gausserès, Junjun Liu, Ewout Foppen, Cécile Tourrel-Cuzin, Ana Rodriguez Sanchez-Archidona, Etienne Delangre, Céline Cruciani-Guglielmacci, Stéphanie Pons, Uwe Maskos, Bernard Thorens, Christophe Magnan, Jamileh Movassat, Kamel Maouche
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomolecules
Subjects:
α7 nAChR
β-cell mass
high glycemia
insulin resistance
fat mass
Online Access:https://www.mdpi.com/2218-273X/10/7/1057

Internet

https://www.mdpi.com/2218-273X/10/7/1057

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