Molecular and cellular mechanisms of itch and pain in atopic dermatitis and implications for novel therapeutics

Abstract Atopic dermatitis is a chronic inflammatory skin disease. Patients with atopic dermatitis experience inflammatory lesions associated with intense itch and pain, which lead to sleep disturbance and poor mental health and quality of life. We review the molecular mechanisms underlying itch and...

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Bibliographic Details
Main Authors: Shawn G Kwatra, Laurent Misery, Claire Clibborn, Martin Steinhoff
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Clinical & Translational Immunology
Subjects:
Online Access:https://doi.org/10.1002/cti2.1390