Nuclear DNA damages generated by reactive oxygen molecules (ROS) under oxidative stress and their relevance to human cancers, including ionizing radiation-induced neoplasia part I: Physical, chemical and molecular biology aspects

Oxidative stress (OS) occurs when the production of reactive oxygen species (ROS) overpowers the body’s natural defence, causing macromolecular damage. The role of OS in cancer initiation will depend on the likelihood of interaction between short lived ROS and nuclear DNA. For this reason, a descrip...

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Bibliographic Details
Main Authors: Robert Nilsson, Ning-Ang Liu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Radiation Medicine and Protection
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666555720300472