Nuclear DNA damages generated by reactive oxygen molecules (ROS) under oxidative stress and their relevance to human cancers, including ionizing radiation-induced neoplasia part I: Physical, chemical and molecular biology aspects
Oxidative stress (OS) occurs when the production of reactive oxygen species (ROS) overpowers the body’s natural defence, causing macromolecular damage. The role of OS in cancer initiation will depend on the likelihood of interaction between short lived ROS and nuclear DNA. For this reason, a descrip...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | Radiation Medicine and Protection |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666555720300472 |