Anti-Tumor Activity of Novel Nimotuzumab-Functionalized Gold Nanoparticles as a Potential Immunotherapeutic Agent against Skin and Lung Cancers

Anti-Tumor Activity of Novel Nimotuzumab-Functionalized Gold Nanoparticles as a Potential Immunotherapeutic Agent against Skin and Lung Cancers

The epidermal growth factor receptor (EGFR) is vital for many different types of cancer. Nimotuzumab (NmAb), an anti-EGFR monoclonal antibody (mAb), is used against some of EGFR-overexpressed cancers in various countries. It targets malignant cells and is internalized via receptor-mediated endocytos...

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Bibliographic Details
Main Authors: Mohammad Anisuzzman, Varsha Komalla, Mariam Abdulaziz M. Tarkistani, Veysel Kayser
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Journal of Functional Biomaterials
Subjects:
nimotuzumab
gold nanoparticle
nanoconjugates
target drug delivery
cellular uptake
cell viability
Online Access:https://www.mdpi.com/2079-4983/14/8/407

Internet

https://www.mdpi.com/2079-4983/14/8/407

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