Ibudilast Mitigates Delayed Bone Healing Caused by Lipopolysaccharide by Altering Osteoblast and Osteoclast Activity

Ibudilast Mitigates Delayed Bone Healing Caused by Lipopolysaccharide by Altering Osteoblast and Osteoclast Activity

Bacterial infection in orthopedic surgery is challenging because cell wall components released after bactericidal treatment can alter osteoblast and osteoclast activity and impair fracture stability. However, the precise effects and mechanisms whereby cell wall components impair bone healing are unc...

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Bibliographic Details
Main Authors: Yuhan Chang, Chih-Chien Hu, Ying-Yu Wu, Steve W. N. Ueng, Chih-Hsiang Chang, Mei-Feng Chen
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
lipopolysaccharide
osteoblast
osteoclast
bone healing
bone bridge
callus bone
Online Access:https://www.mdpi.com/1422-0067/22/3/1169

Internet

https://www.mdpi.com/1422-0067/22/3/1169

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