A systematically biosynthetic investigation of lactic acid bacteria reveals diverse antagonistic bacteriocins that potentially shape the human microbiome

A systematically biosynthetic investigation of lactic acid bacteria reveals diverse antagonistic bacteriocins that potentially shape the human microbiome

Abstract Background Lactic acid bacteria (LAB) produce various bioactive secondary metabolites (SMs), which endow LAB with a protective role for the host. However, the biosynthetic potentials of LAB-derived SMs remain elusive, particularly in their diversity, abundance, and distribution in the human...

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Bibliographic Details
Main Authors: Dengwei Zhang, Jian Zhang, Shanthini Kalimuthu, Jing Liu, Zhi-Man Song, Bei-bei He, Peiyan Cai, Zheng Zhong, Chenchen Feng, Prasanna Neelakantan, Yong-Xin Li
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Microbiome
Subjects:
Lactic acid bacteria
Biosynthetic gene clusters
Secondary metabolites
Bacteriocins
Human microbiome
Vaginal microbiome
Online Access:https://doi.org/10.1186/s40168-023-01540-y

Internet

https://doi.org/10.1186/s40168-023-01540-y

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