The role of B cells in immune cell activation in polycystic ovary syndrome

The role of B cells in immune cell activation in polycystic ovary syndrome

Variations in B cell numbers are associated with polycystic ovary syndrome (PCOS) through unknown mechanisms. Here, we demonstrate that B cells are not central mediators of PCOS pathology and that their frequencies are altered as a direct effect of androgen receptor activation. Hyperandrogenic women...

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Bibliographic Details
Main Authors: Angelo Ascani, Sara Torstensson, Sanjiv Risal, Haojiang Lu, Gustaw Eriksson, Congru Li, Sabrina Teschl, Joana Menezes, Katalin Sandor, Claes Ohlsson, Camilla I Svensson, Mikael CI Karlsson, Martin Helmut Stradner, Barbara Obermayer-Pietsch, Elisabet Stener-Victorin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
polycystic ovary syndrome
androgens
B cells
immune
Online Access:https://elifesciences.org/articles/86454

Internet

https://elifesciences.org/articles/86454

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