Discovering networks of perturbed biological processes in hepatocyte cultures.

The liver plays a vital role in glucose homeostasis, the synthesis of bile acids and the detoxification of foreign substances. Liver culture systems are widely used to test adverse effects of drugs and environmental toxicants. The two most prevalent liver culture systems are hepatocyte monolayers (H...

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Bibliographic Details
Main Authors: Christopher D Lasher, Padmavathy Rajagopalan, T M Murali
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3016309?pdf=render