Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission
The KEAP1-Nrf2-ARE antioxidant system is a principal means by which cells respond to oxidative and xenobiotic stresses. Sulforaphane (SFN), an electrophilic isothiocyanate derived from cruciferous vegetables, activates the KEAP1-Nrf2-ARE pathway and has become a molecule-of-interest in the treatment...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-04-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231716302750 |