Integration of Metabonomics and Transcriptomics Reveals the Therapeutic Effects and Mechanisms of Baoyuan Decoction for Myocardial Ischemia

Integration of Metabonomics and Transcriptomics Reveals the Therapeutic Effects and Mechanisms of Baoyuan Decoction for Myocardial Ischemia

Myocardial ischemia (MI) is an escalating public health care burden worldwide. Baoyuan decoction (BYD) is a traditional Chinese medicine formula with cardioprotective activity; however, its pharmacological characteristics and mechanisms are obscured. Herein, a multi-omics strategy via incorporating...

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Bibliographic Details
Main Authors: Zhiyong Du, Zeliu Shu, Wei Lei, Chun Li, Kewu Zeng, Xiaoyu Guo, Mingbo Zhao, Pengfei Tu, Yong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
myocardial ischemia
traditional Chinese medicine formula
Baoyuan decoction
pharmacodynamics
metabonomics
transcriptomics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00514/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00514/full

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