Development of machine learning models for the prediction of the skin sensitization potential of cosmetic compounds

Background To enhance the accuracy of allergen detection in cosmetic compounds, we developed a co-culture system that combines HaCaT keratinocytes (transfected with a luciferase plasmid driven by the AKR1C2 promoter) and THP-1 cells for machine learning applications. Methods Following chemical expos...

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Dades bibliogràfiques
Autors principals: Wu Qiao, Tong Xie, Jing Lu, Tinghan Jia
Format: Article
Idioma:English
Publicat: PeerJ Inc. 2024-12-01
Col·lecció:PeerJ
Matèries:
Accés en línia:https://peerj.com/articles/18672.pdf