Development of machine learning models for the prediction of the skin sensitization potential of cosmetic compounds

Background To enhance the accuracy of allergen detection in cosmetic compounds, we developed a co-culture system that combines HaCaT keratinocytes (transfected with a luciferase plasmid driven by the AKR1C2 promoter) and THP-1 cells for machine learning applications. Methods Following chemical expos...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wu Qiao, Tong Xie, Jing Lu, Tinghan Jia
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: PeerJ Inc. 2024-12-01
Σειρά:PeerJ
Θέματα:
Διαθέσιμο Online:https://peerj.com/articles/18672.pdf